My goal for these camera settings is to improve the "lens-sensor relationship" by adjusting the contrast, sharpness, noise reduction and color with the result that it produces an image that looks less "digital" and more "organic" (more like film, etc). The first step is to apply these settings while shooting (produces an image that looks pretty good straight out of camera) but keep in mind there may need to be slight color grading (or a LUT) applied to finalize each shot.